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GrahamPackham and his research group at the University of Southampton in collaboration with Aquinox. Titled Chemical Activation of the SHIP1 Inositol Lipid Phosphatase: A Novel Therapeutic Strategy to Suppress B-cell Receptor Signaling and CXCR4 Expression in Malignant Human B Cells, the abstract can be found on the ASH website at www.hematology.org . Poster Presentation The abstract supports the hypothesis that chemical SHIP1 activation is sufficient to suppress BCR-mediated signaling in chronic lymphocytic leukemia cells, acting, at least in part, by decreasing activation of the AKT pathway. In addition, SHIP1 activation results in CXCR4 down-modulation in CLL cells, a response not observed with direct PI3K inhibition. Title:Chemical Activation of the SHIP1 Inositol Lipid Phosphatase: A Novel Therapeutic Strategy to Suppress B-cell Receptor Signaling and CXCR4 Expression in Malignant Human B Cells (Abstract #2037) Lead Investigator: Prof.GrahamPackhamBSc (Hons), PhD, Professor of Molecular Oncology within Medicine at the University of Southampton. Session Name: 642. CLL: Therapy, excluding Transplantation: Poster I Session Date: Saturday,December 3, 2016 Session Time:5:30 p.m. 7:30 p.m. PT About Aquinox Pharmaceuticals, Inc.find out here now

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( FL ) will host a conference call at 9:00 AM ET on November 18, 2016, to discuss Q3 16 earnings results. To access the live webcast, log on to http://www.footlocker-inc.com To listen to the call, dial 1-800-941-7616 (US) or +44 208-196-2142 (International). CLOSEX Edit Favorites Enter up to 25 symbols separated by commas or spaces in the text box below. http://boogieleaderfsv.intelelectrical.com/a-detailed-analysis-of-locating-key-issues-in-chiropody-bunionsThese symbols will be available during your session for use on applicable pages. Select the background color of your choice: Black Select a default target page for your quote search: Real-Time Interactive Charts Default Setting Please note that once you make your selection, it will apply to all future visits to NASDAQ.com. If, at any time, you are interested in reverting to our default settings, please select Default Setting above. If you have any questions or encounter any issues in changing your default settings, please email isfeedback@nasdaq.com . CLOSEX Please confirm your selection: You have selected to change your default setting for the Quote Search. This will now be your default target page; unless you change your configuration again, or you delete your cookies.

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